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(JCA-0709) Healthy Volunteers for the Human Genetics of Infectious Diseases (HGID)


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Healthy Volunteers for the Human Genetics of Infectious Diseases (HGID)

Principal Investigator:
Jean-Laurent Casanova MD, PhD

Investigators:
Shen-Ying Zhang MD, PhD
Emmanuelle Jouanguy PhD
Stephanie Boisson-Dupais PhD
Bertrand Boisson PhD

Contact Information:
Clinical Research Support Office
The Rockefeller University
1230 York Ave.
New York, NY 10065
Telephone: 1.800.RUCARES
Email: RUCARES@Rockefeller.edu
Enrollment Status:
Open to Enrollment

Brief Summary of Protocol:
Dr. Casanova’s laboratory is studying a rare defect in the ability to fight a serious infectious disease. The types of research include the study of hepatitis, herpes simplex encephalitis, mycobacterial disease, salmonellosis, adenovirus, respiratory viral diseases, invasive pneumococcal diseases, etc. It is not known why these occur, but it is likely that there is a change in a collection of genes that causes an increased risk for this condition. The reason for doing this research is to identify these genes that cause predisposition to develop severe infectious disease. We are trying to gain a better understanding of infectious diseases.

Approximately, 500 people will take part in the research study. This study will last approximately 10 years.



Detailed Description of Protocol:
This study involves donations of blood. You may be asked to return for repeat blood draws up to 5 times per year.



What specifically makes a person eligible for the study?
You may be eligible to enter this study:

- Healthy volunteer as defined as no history of any severe and/or active infectious disease
- Subject reports good venous access

Gender:
Both

Age(s):
12-100

Children permitted to participate:
Yes

Potential Benefits.....
There will be no benefit to you from taking part in this research study. Instead, others may benefit in the future from what we learn from this study.



Compensation:
Compensation is provided. If you are a child, you will receive compensation in the form of a gift card to Toys “R” Us.