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(NBO-0863) Endocannabinoids and shift work

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Role of Endocannabinoid Signaling on Sleep and Wakefulness in NYC Day and Night Shift Workers

Principal Investigator:
Nicole Bowles


Contact Information:
Recruitment Specialist
1230 York Ave
New York, NY 10065
Telephone: 1800RUCARES
Enrollment Status:
Closed to Enrollment

Brief Summary of Protocol:
The reason for doing this research: In this study we are interested in how the nontraditional work hours and light exposure experienced by shift workers impact sleep-wake patterns. Decreased alertness, motor coordination (body movement), cognitive performance (thinking), sleep disturbances, and changes in appetite are characteristics of irregular work or shift work schedules. Endocannabinoids, chemical signals produced in the body regulate memory, appetite, pain perception, and sleep. It is unclear how shift work may alter these chemical signals. This study aims to better understand the contribution of endocannabinoid signals as they relate to sleep and appetite.

Detailed Description of Protocol:

What specifically makes a person eligible for the study?
You may be eligible to enter this study:

Must work in New York City, and be willing to provide work history, and work a consistent day or night schedule of at least 4 consecutive shifts per week for 6 months prior and over the course of the study (hours between 7am and 7pm; 8pm and 8am). Cannot have a BMI > 30 Cannot drink > 300 mg caffeine/day (3 regular cups of coffee, 5 cans of caffeinated soda, 1.5 energy shoots) Must not have taken vacation or sick time for > 4 consecutive days for one month prior to initiating study Cannot have traveled across 3 or more time zones within one month of initiating study. Cannot actively recreational drug use (verbal communication of such is sufficient) Cannot have an active cold or seasonal allergies



Children permitted to participate:

Potential Benefits.....
no benefit

compensation is provided