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(THU-0887) Aspartame

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Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption

Principal Investigator:
Thomas Huber PhD


Contact Information:
Recruitment Specialist
1230 York Ave
New York, NY 10065
Telephone: 1800RUCARES
Enrollment Status:
Open to Enrollment

Brief Summary of Protocol:
Artificial sweeteners frequently used to sweeten some diet drinks and foods and are often believed to be a safer and healthier than sweeteners such as natural sugars and highfructose corn syrup. Studies have shown that some artificial sweeteners like those in diet soda can cause changes how the body responds to sugar and may increase the chance of obesity, type 2 diabetes, and other diseases. In this study, we plan to see if the most common artificial sweetener, aspartame (also known as Equal or NutraSweet), changes how the body responds to sugar and if these changes can be reversed when aspartame is removed from a daily diet.

Detailed Description of Protocol:

What specifically makes a person eligible for the study?
You may be eligible to enter this study:

- BMI between 21-29 - Primary dietary sweetener is aspartame; consumes at least 36 ounces of diet soda in which aspartame is a primary ingredient (Diet Coke or Diet Dr Pepper) a day for at least 6 months duration prior to study enrollment - Does not have diabetes - Does not have an abnormal thyroid - No history of cardiac disease



Children permitted to participate:

Potential Benefits.....
No known benefit

compensation is provided