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(DRO-0907) Past or Acute Zika virus infection


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Identification and Characterization of ZIKV-Neutralizing Antibodies and ZIKV Isolates in Individuals with Past or Acute Zika Virus Infection

Principal Investigator:
Davide Robbiani MD, PhD

Investigators:
Margaret MacDonald M.D., PhD
Marina Caskey M.D.

Contact Information:
Recruitment Specialist
1230 York Avenue
New York, NY 10065
Telephone: 1800RUCARES
Email: RUCARES@Rockefeller.edu
Enrollment Status:
Open to Enrollment

Brief Summary of Protocol:
  • Zika virus is a flavivirus transmitted to humans through the bite of an infected mosquito, or by sexual contact with an infected individual.
  • Zika virus infection can produce a mild, febrile illness, which can also be associated with a skin rash and joint pain.
  • Currently there is no effective treatment against Zika virus infection, and its diagnosis remains a challenge.
  • The ultimate goal of this protocol is to characterize antibody responses against Zika virus in individuals with known previous Zika virus infection.




Detailed Description of Protocol:




What specifically makes a person eligible for the study?
You may be eligible to enter this study:

PAST INFECTION:
If you have:
-a history of travel to an area with active mosquito-borne transmission of Zika virus OR sexual exposure to a partner diagnosed with Zika virus infection
AND
-a history of symptoms compatible with Zika virus infection after the travel or sexual exposure.

ACUTE INFECTION:
If you have:
-a history of travel to an area with active mosquito-borne transmission of Zika virus OR sexual exposure to a partner diagnosed with Zika virus infection
AND
-symptoms compatible with Zika virus infection within 7 days of screening.

Gender:
Both

Age(s):
18-100

Children permitted to participate:
No

Potential Benefits.....
There is no direct benefit to you for taking part in this study. However, the information that we gain from this study may help others in the future.



Compensation:
compensation is provided