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(JHS-0914) Study to Improve Smell Assessment


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Toward efficient and convenient olfactory assessment

Principal Investigator:
Julien W. Hsieh MD

Investigators:
Leslie B. Vosshall Ph.D.

Contact Information:
Recruitment Specialist
1230 York Avenue
New York, NY 10065
Telephone: 1800RUCARES
Email: RUCARES@Rockefeller.edu
Enrollment Status:
Completed/Closed

Brief Summary of Protocol:
A person’s sense of smell is not often thought of as important to their overall health. However, the loss of smell impacts the eating habits, mental health, and safety of those affected, and can be an early symptom of a neurological conditions such as Parkinson’s and Alzheimer’s diseases. Despite the importance of this sensory system, smell assessment is largely underutilized in private medical practice. To screen this condition in the population, the development of an effective smell test is not enough. Such a smell test must also be convenient to administer in primary care. Currently, smell assessment is time-consuming, taking up to one hour, outside of what can realistically be administered in a primary care environment. The goal of this project is to create an efficient method to evaluate the sense of smell without compromising testing reliability and accuracy. We hope that this work will optimize smell assessment in all clinical settings therefore improving the management of disorders related to smell dysfunction.



Detailed Description of Protocol:
Participation includes: -2 visits to Rockefeller University -Smell testing



What specifically makes a person eligible for the study?
You may be eligible to enter this study:

Healthy Volunteers: -No allergies to odors or fragrances -No asthma -No history of nasal or brain surgery Volunteers with Smell Dysfunction: -Not receiving treatment for smell loss

Gender:
Both

Age(s):
18-100

Children permitted to participate:
No

Potential Benefits.....
No known benefit



Compensation:
Compensation is provided